The impact of TIO
TIO is a progressive disease that is commonly misdiagnosed1,2
TIO symptoms are nonspecific, progressive, and can lead to long-term disabilities. Patients may experience misdiagnosis or delayed diagnosis for several years, so it is vital that TIO is treated as soon as possible.1,2
Presentation of TIO can vary
Excess FGF23 is the underlying cause of symptoms for patients with TIO. While the presentation and severity of symptoms vary, bone pain may be their initial symptom. This often starts in the lower limbs, most commonly in the feet and ankles.1,3 Other symptoms of TIO can include, but are not limited to1,3:
CRYSVITA has not been studied or approved for treating muscle pain, bone pain, or fatigue.
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